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Vanish centers on a Hispanic American’s search (Luis Ramón Morales) in Ecuador in 1998 for his younger 24-year-old brother Rob after missing his plane back to Miami. Luis, a 28-year-old engineer from Dallas, would have to travel through the Amazon jungle and meddle in his brother’s love affair before reaching an end he never expected. The disappearance would ultimately pull their parents, doña María de los Ángeles and don Roberto, Peruvian immigrants living in south Florida, into the hunt.