This book is a primer on how information is processed in a typical mammalian brain. To talk about these ideas intelligently, the reader needs to use ideas from mathematics, computer science and many areas of science. Intertwining these normally separate areas into a coherent whole provides an introduction to modern interdisciplinary work. In the book, we develop carefully how an excitable neuron collects information from many sources and then outputs a single voltage pulse which carries a variety of signaling information. Our modeling efforts are based on the use of MatLab (although octave is just fine) so it should be easy to do experiments yourself. We cover the usual basics of axonal pulse propagation including Hodgkin-Huxley models, dendritic cable models, first and second messenger signalling system abstractions and so forth. This book provides a good foundation towards building models of cognition which may be used for models of depression and other forms of dysfunction.
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