Shop

Large Scale Methods to Enumerate Extreme Rays and Elementary Modes (b/w print)

eBook (PDF), 168 Pages
This item has not been rated yet
Price: Free
A major challenge in systems biology is to improve the understanding of complex metabolic networks. Here, we focus on structural analysis since it requires mainly reaction stoichiometries, in contrary to detailed dynamic methods that are often limited by insufficient knowledge on mechanisms and parameters. Thermodynamic reaction constraints and the steady state assumption reduce the solution space for valid reaction fluxes to a convex polyhedral cone. Pathway analysis methods aim at finding a unique generating set for the flux cone---called extreme rays or elementary modes. We describe critical aspects for an efficient implementation of the double description method for large scale application. The efficiency of introduced techniques is demonstrated with large application examples from combinatorics and systems biology.
Available in PDF Format

Ratings & Reviews

Log in to review this item
There are no reviews for the current version of this product
Refreshing...
There are no reviews for previous versions of this product
Refreshing...

Product Details

Published
September 28, 2011
Language
English
Pages
168
File Format
PDF
File Size
18.2 MB

Formats for this Ebook

PDF
Required Software Any PDF Reader, Apple Preview
Supported Devices Windows PC/PocketPC, Mac OS, Linux OS, Apple iPhone/iPod Touch... (See More)
# of Devices Unlimited
Flowing Text / Pages Pages
Printable? Yes
Report This Content to Lulu >

Moderation of Questionable Content

Thank you for your interest in helping us moderate questionable content on Lulu. If you need assistance with an order or the publishing process, please contact our support team directly.

How does this content violate the Lulu Membership Agreement?

Keywords

Listed In

More From Marco Terzer