Fluorinating Reagents

eBook (PDF), 138 Pages
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The area of organofluorine chemistry often requires special techniques associated with the handling of fluorinating agents. The introduction of fluorine into bioactive molecules often results in significant changes in their chemical, physical, and biological properties. Fluorine uniquely affects the property of organic molecules due to the fluorine atom’s blocking effect in metabolic transformations and mimicking of enzyme substrates, and then increases the molecular lipophilicity to enhance bioavailability. Approximately 30% of all agrochemicals and 20% of all pharmaceuticals contain fluorine. Therefore, fluorinating reagents are useful tools for the synthesis of pharmaceutical and agricultural compounds. To facilitate the synthesis of fluorinated molecules, here in this book we have described a range of reagents and building blocks that are easier to handle than previous caustic sources of fluorine.
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Product Details

First Edition
May 10, 2015
File Format
File Size
1.27 MB

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Required Software Any PDF Reader, Apple Preview
Supported Devices Windows PC/PocketPC, Mac OS, Linux OS, Apple iPhone/iPod Touch... (See More)
# of Devices Unlimited
Flowing Text / Pages Pages
Printable? Yes
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