Search Results: 'genetic diseases'
Genetics of Gaucher Disease
This review article discusses genetic, clinical and evolutionary aspects of Gaucher disease. Gaucher disease is an autosomal recessive disorder of lipid storage. It is very common worldwide. This... More > review covers traditional laboratory and genetic testing for Gaucher disease, with specific attention given to the effectiveness and limitations of these tests. Treatment options, including experimental gene therapy, are covered as well. We explored the prevalence of this disorder and compared rates of occurrence of different mutations among different ethnic groups. Special attention has been given to the evolutionary aspect of Gaucher disease – we discussed anthropologic and animal studies and analyzed the most popular hypothesis of the selective advantage of Gaucher disease. This review article also discusses the rates of occurrence of neurological, pulmonary and cardio-vascular disease in Gaucher disease patients.< Less
Genetics of Cystic Fibrosis: A Comprehensive Review
This review article is focused on genetic and clinical characteristics of cystic fibrosis (CF), a hereditary disorder that causes electrolyte and fluid transport imbalances. Cystic fibrosis has been... More > considered primarily a disease of European population. This article provides statistics from the latest studies and explores recent data from WHO to demonstrate an important concept - cystic fibrosis affects all races and ethnic groups, but due to the lack of awareness, it is often unrecognized. This review covers in-depth classification of types of CF and discusses adult, neonatal and prenatal screening, including newest genetic screening. A new concept of evolutionary advantage of some hereditary conditions has been recently introduced in medical sciences. Using the data from latest anthropologic and clinical studies, we provide evidence in support of the hypothesis that gene for cystic fibrosis developed under evolutionary pressure and confers beneficial effect to the gene carriers.< Less
Skin Diseases of Rabbits
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This book results from requests from rabbit owners and veterinarians who were seeking reliable, up to date information about skin diseases and their treatment. Material related to rabbits is, indeed,... More > not readily available, or limited to a chapter in rabbit medicine or veterinary books. Here, a comprehensive approach aims at describing a skin disorder and its rabbit-specific clinical signs, diagnosis, and rabbit-safe treatment options. The book chapters deal with rabbit skin anatomy, examination of rabbits, and viral, bacterial, fungal, parasitic, mechanical, genetic, hormonal, immune and neoplastic diseases. Pen drawings illustrate the different disorders.
The collaboration with a veterinarian and a rabbit owner has contributed to the clarity and the quality of the provided information. Hopefully “Skin Diseases of Rabbits” will appeal to the small animal and exotic practitioner, veterinary students, veterinary nurses, and owners, and become a helpful addition to their handling and treating rabbits.< Less
DEVELOPING A DISEASE RESISTANT POTATO
This is a brief analysis of the basics of genetics as it applies to the potatos and what has to be done to develop a disease resistant potato.
Natural Products, Chemical Compounds, and Gene Targets for Weight Loss: Discoveries from Genetic Interactions
Body weight is decided by the balance between food intake and energy expenditure. Some genes have been found to be important signal molecules in the cells and play crucial roles in the central... More > regulation of food intake, feeding behavior, and energy homeostasis. These genes are potential targets and biomarkers for the treatment of obesity and associated diseases such as diabetes and cardiovascular diseases. Many natural products, such as extracts and compounds from fruits and herbs, have weight loss effects and can protect against high-fat-diet induced obesity. These natural products and compounds can be used in food ingredients, diet therapy, or drug components for the treatment of obesity. Recent scientific studies have elucidated the molecular mechanisms of these products. The weight loss effects of these products may be mediated through adjusting genes involved in energy homeostasis. (Journal of Personalized and Systems Medicine)< Less
CLONING 666 - THE NEW AGE OF SHADOW CLONING, STEM CELLS, & GENETIC ENGINEERING – A List Of Bio Companies Studying Regeneration
CHAPTER 1 INVITROGEN AND APPLIED
CHAPTER 2 EMBRYONIC STEM CELL RESEARCH
WHAT’S THE PROBLEM?
CHAPTER 3 CLONING DEBATES
CHAPTER 4 STEM CELL RESEARCH DEBATES
CHAPTER... More > 5 BIOSPACE LIFE TECHNOLOGIES CHAPTER 6 REGENERATIVE MEDICINE CURING
DISEASES AND REPAIRING TISSUE DAMAGE THROUGH STEM CELL TECH?
CHAPTER 7 SUNSTAR CONCLUSION ABOUT HOW
THE DARK SIDE OF REGENERATIVE
MEDICINE HELPS TO KEEP THE
CHAPTER 8 GENESIS 6 – FALLEN ANGELS MARRYING
MORTAL WOMEN AND A SCIENTIFIC
EXPLANATION FOR HOW THEIR DNA
REPRODUCED GIANTS FOR CHILDREN WHO WERE HEROES OF OLD, MEN OF RENOWN, BUT BECAME EVIL.
CHAPTER 9 CLONING 666< Less
Complete Medical Guide for Disease Volume V: Ankylosing Spondylitis
Ankylosing spondylitis (AS, from Greek ankylos, stiff; spondylos, vertebrae), previously known as Bekhterev's disease, Bekhterev syndrome, and Marie-Strümpell disease, is a chronic inflammatory... More > disease of the axial skeleton with variable involvement of peripheral joints and nonarticular structures. AS is a form of spondyloarthritis, a chronic, inflammatory arthritis and autoimmune disease. It mainly affects joints in the spine and the sacroiliac joint in the pelvis, and can cause eventual fusion of the spine.
It is a member of the group of the spondyloarthropathies with a strong genetic predisposition. Complete fusion results in a complete rigidity of the spine, a condition known as "bamboo spine". As of 2012, no cure is known for AS, although treatments and medications are available to reduce symptoms and pain.< Less
Complete Medical Guide for Disease Volume XIX; Marfan Syndrome
Marfan syndrome (also called Marfan's syndrome) is a genetic disorder of the connective tissue. People with Marfan's tend to be unusually tall, with long limbs and long, thin fingers.
The syndrome... More > is inherited as a dominant trait, carried by the gene FBN1, which encodes the connective protein fibrillin-1. People have a pair of FBN1 genes. Because it is dominant, people who have inherited one affected FBN1 gene from either parent will have Marfan syndrome.
Marfan syndrome has a range of expressions, from mild to severe. The most serious complications are defects of the heart valves and aorta. It may also affect the lungs, the eyes, the dural sac surrounding the spinal cord, the skeleton and the hard palate.
In addition to being a connective protein that forms the structural support for tissues outside the cell, the normal fibrillin-1 protein binds to another protein, transforming growth factor beta (TGF-β).< Less