On a summer afternoon in Albuquerque, a bus departs for Los Angeles and three of the passengers, unfamiliar with one another, are unaware of how entangled their paths will soon become. Empty-nester Martha Gregory, lacking experience in a world beyond her husband and home in New Mexico, is lured by a pre-paid ticket to reconnect with her younger sister. Handsome media executive Marc Greensweig, deigns to return from a business trip by bus, fortified by the free pass to the top of the corporate ladder awaiting him at home. Emanuel Montoya, recent college grad fleeing a painful breakup, eagerly embraces the new life that beckons when offered a place to stay in West Hollywood. Meanwhile, simmering in L. A. is William Miller, a lonely security guard, fighting a losing battle to distance himself from the troubling voices in his head. As if guided by an unseen hand, each must respond to a crisis in which their actions will ultimately determine whether second chances really do exist…

Thirty years after having been orphaned and raised apart without awareness of one another three long lost brothers join forces for the sake of the sister who needs them and, as they become acquainted with one another, piece together the circumstances of their childhood. As they delve into their past, it becomes clear that each man presently stands at a personal crossroads. At every turn, pieces of the puzzle bring them closer to finding their sister—and finding themselves.