The annual Bobby Jones Chiari & Syringomyelia Foundation (Bobby Jones CSF) Research Colloquium facilitates information-sharing and research dissemination between scientists, engineers, clinicians, and other experts who rarely have the opportunity to come together in other forums. This multidisciplinary look at the same problem helps clinicians to think outside-the-box when it comes to disorders such as Chiari malformation, syringomyelia and related disorders. The 2020 presentations span multiple topics, ranging from cognitive responses to Chiari surgery and neuro-behavioral considerations to new genetic discoveries. The chapters in these proceedings were originally presented orally and have been adapted to the written word. You can learn more about the Bobby Jones CSF at bobbyjonescsf.org.