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Flanking Parkinson's disease: further evidence pointing to EGLN genes as well as RPS27, RPL7, RPL23 and KRT genes/pseudogenes playing a central role in Parkinson's disease and schizophrenia aetiology.

ByJohn Neville

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In many CNV disorders which cause increased risk of schizopnrenia, it has been noted that there are flanking genes, particularly RPL23, RPL7, RPS27 and KRT pseudogenes, which have a direct connection to EGLN3 gene function or genes that themselves flank EGLN3. It was additionally noted that three out of the four Parkinson's disease genes - PRKN, PARK7, PINK1 and LRRK2 - were flanked by one or more of these same four pseudogenes. It was predicted that a more thorough investigation of Parkinson's disease genes would be expected to throw up similar results. Here further Parkinson's genes have been considered. A large number of these further Parkinson's disease genes are flanked by either a RPL7, RPL23, RPS27 and/or a KRT pseudogene.

Details

Publication Date
Mar 21, 2020
Language
English
ISBN
9780244574000
Category
Science & Medicine
Copyright
All Rights Reserved - Standard Copyright License
Contributors
By (author): John Neville

Specifications

Pages
40
Binding
Paperback
Interior Color
Black & White
Dimensions
Pocket Book (4.25 x 6.875 in / 108 x 175 mm)

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