Molecular Biology of the Flavivirus

Flaviviruses constitute a family of linear, single-stranded RNA(+) viruses. They cause approximately 70 different diseases which have a major impact on national economies and health authorities worldwide. With contribution from internationally acclaimed authors such as Ernest Gould and Hubert Blum, this book reviews the most significant cutting edge discoveries in the flavivirus field. Aspects of molecular biology common to flaviviruses are explored in depth. Topics include the evolution and function of flavivirus RNA, flavivirus replication, laboratory diagnosis and vaccine development. Individual chapters are devoted to the molecular biology of yellow fever virus, dengue virus, Japanese encephalitis virus, and hepatitis virus C virus. Essential reading for all flavivirus researchers and a recommended text for all virology laboratories.