Ovariální hyperstimulační syndrom v programu asistované reprodukce

BACKGROUND: Aim of the study is to define the risk factors of ovarian hyperstimulation syndrome onset during assisted reproduction treatment using in vitro fertilization technique. Exploratory computer analysis of electronically stored data about assisted reproduction treatment cycles in clinical registry with the use of data mining system. RESULTS: Significantly higher incidence of a clinically important form of ovarian hyperstimulation syndrome development was observed among patients under 30 years old who were affected by hyperstimulation syndrome in previous treatment cycles. We can predict a higher risk in patients with oligomenorrhoea and in cases of immunological and andrological sterility factor. Higher incidence of clinically significant form of hyperstimulation syndrome is noticed with stimulation protocols with highly effective gonadotrophine hormones where the total dose of gonadotrophins is greater than 1125 IU and maximum 17-beta estradiol levels are greater than 20 nmol/l.