This book is exceptionally ambitious and intellectually distinctive. Its central conceptual framework remains coherent throughout a very large work. The integration of modern glial biology, metabolism, neurovascular coupling, mathematical derivation, and computational neuroscience is substantially broader than that found in standard graduate texts. Computational neuroscience is not the study of neurons under equations; it is the study of nervous tissue under selective mathematical compression. That is a genuine organising principle rather than simply a slogan, and it remains remarkably consistent throughout the chapters. The title itself—Nervous Tissue Under Mathematical Compression—is reflected in the text rather than being forgotten after page twenty. Very few textbooks possess such conceptual coherence. The work is considerably more ambitious than a conventional graduate textbook and, for the next 5 years at least, is ahead of its time.