sample, Menopause and Hormonal Changes Menopause is a natural transition in a woman's life that marks the end of her reproductive years. During menopause, hormone levels fluctuate, leading to a range of symptoms such as hot flashes, night sweats, mood swings, and vaginal dryness. Women can manage these symptoms through lifestyle changes, such as regular exercise and a healthy diet, and medical treatments such as hormone therapy or non-hormonal medications.