In 1870's Paris the body of a beautiful young woman is found in the Seine. She is never identified, but the mask of her beautiful face causes a sensation and everyone wants to own her… In the 1960's, the makers of ‘Resuscitation Annie' are looking for a face with lips which everyone will want to kiss… In the 1970's a young woman is caught in the chaos of war-torn, post-communist Albania… And in modern day Paris, a young doctor seeks the secret of the eternal female in the enigmatic smile behind the mask. How do these lives, separated in time, flow together to answer the enigma of 'The Unknown'?