Oreste M. G. Debernardi, born in Alessandria, Italy, relational artist and Italian writer assimilated for style to self-narrative paradigm, educated in Semiotics, conducts an original research in the field of neuro-sciences, studying in particular the mechanisms regulating the cognitive and affective activities. Some of his books, sharing the results of his relational works, offer a good representation of the dynamics which born when we are involved in emotional activation or moved by the unconscious.  The results of his researches on learning and affectivity are applied to the study on the interaction of the hypothalamic system with the immune system. His experiences and his projects, social and artistic, deepen the ways to learn on the emotional plan.